Wild lettuce, also known as Lactuca virosa, is a plant traditionally used in herbal medicine, with potential benefits when prepared as an internal tincture. The milky sap from wild lettuce contains the medicinal properties, making it a valuable component for tincture preparation[1]. Although there are no standard doses for wild lettuce tincture due to the lack of FDA approval and human research, it has been traditionally used for pain relief and sedative effects[2]. In traditional use, the dosage typically ranges from 12–24 drops, two or three times daily for tincture format[3].

Research and trials involving animal subjects have shown promising results for wild lettuce extracts in providing pain relief and sedation[4]. However, it's important to note that foraging for wild lettuce and preparing tinctures should be approached with caution and with a good understanding of plant identification, as misidentification can lead to harmful consequences.

Sources:

1. https://www.primalsurvivor.net/wild-lettuce-extract/

2. https://www.verywellhealth.com/the-benefits-of-wild-lettuce-88661

3. https://www.botanicalinstitute.org/wild-lettuce/

4. https://7song.com/wild-lettuce-preparing-a-concentrated-tincture/